9/8 Journal Club

Last week our researchers and physicians discussed a paper about bile acid metabolites, and their implications in MS research. Bile acid metabolites are signaling molecules that work throughout the central nervous system, and researchers identified lower levels of these metabolites in MS patients. Supplementing with a specific acid known as TUDCA was shown to reduce inflammation and disease severity in preliminary research. These results identify dysregulated bile acid metabolism as a potential therapeutic target in MS.