Journal Club Recap: January 4, 2019

January 4, 2019: Our experts sat down to discuss a paper on disease-specific oligodendrocyte lineage cells and their relationship with MS.

Disease-specific Oligodendrocyte Lineage Cells Arise in Multiple Sclerosis 

Researchers have found that a subset of oligodendrocytes, the cells that produce myelin, and their progenitor cells (OPCs) in the animal model of MS have more in common with immune cells than previously thought. These disease-specific oligodendrocytes are also present in the active lesions of the brains of patients with MS and these cells express genes thought to be associated with MS susceptibility. During this session of Journal Club, our team discussed that the clinical applications of this discovery require further research.